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As researchers continue to uncover the many roles of GLP-1, GLP-1R, and synthetic GLP-1RAs in systems beyond the endocrine, potential pharmacologic applications of GLP-1RAs in a variety of pathology are becoming increasingly clear
These results support early genetic screening in children with severe, early-onset obesity and the use of precision therapies like Setmelanotide in genetically confirmed MC4R-pathway disorders
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The biological activity of CRMP2 depends on posttranslational modifications
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