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reported a 40% decrease in IGF-1 protein levels during the early stages of tendon healing compared to intact tendons, with levels peaking at 4 weeks and remaining elevated through 8 weeks post-injury (Dahlgren et al., 2005)
Recently, the interaction between forkhead box O4 (FOXO4) and p53 has received considerable attention as a target for senescent cells
Sin embargo, su coste elevado puede limitar el acceso continuado , y su eficacia en alcanzar concentraciones teraputicas en el sistema nervioso central an est bajo estudio
Stice et al., 2008
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