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AOD9604 did not stimulate the production of IGF-1 in any of the systems studied, and elicits its fat-reducing effects without inducing insulin resistance a key pharmacological distinction from intact hGH that makes it a uniquely clean research tool for studying lipolytic mechanisms in isolation

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Semaglutide or Tirzepatide: GLP-1 receptor agonists work through entirely different mechanisms (appetite suppression, glucose regulation, delayed gastric emptying) compared to AOD-9604s direct lipolytic effects

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