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A study at the University of Adelaide looking at ways to trigger release of the gut hormone GLP-1 - the hormone upon which weight-loss drugs are based - previously found that giving a bile acid enema to healthy volunteers triggered release of GLP-1, but had the unintended consequence of causing diarrhea
This section is mandatory reading before working with MT1 in any laboratory setting
GI side effects may temporarily return during this transition
NNC0165-1875 has recently completed a phase 2 trial in combination with semaglutide 2.4 mg once weekly (NCT04969939), but results are not currently available
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