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That changed in November 2025, when Novo and Lilly announced an agreement with the White House to significantly drop prices for self-pay patients and extension of Medicare coverage for weight loss starting April 2026
Possible Side Effects and Complications Both tirzepatide and semaglutide can cause side effects, especially in the early stages of treatment
It can be used alone or in combination with other diabetes medication(s)
Roughly every four to six weeks while the amount is being escalated, to review glucose, kidney function, and side-effect tolerance
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