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Carvone is a mild skin sensitizer while limonene is a well-known one

In summary, additional research is needed to understand the intricate molecular mechanisms of p53 in regulating senescence in order to optimize the efficacy and safety for clinical applications

10.1016/j.phymed.2022.154319 45 HuangJ.LiuD.WangY.LiuL.LiJ.YuanJ.et al (2022b)