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GRAS status does not equal drug approval, but it does indicate that the regulatory body considered the compound safe for human consumption at the doses tested
It can also be used as an auxiliary treatment after bariatric surgery to improve postoperative skin laxity and fat residue
The metabolic adaptations that occur are limited to the enhanced expression of beta-3 adrenergic receptors in adipose tissue, which actually represents a favorable metabolic improvement rather than a dependence-creating change
What exists is literature discussing why researchers have theorized these pairings might be of interest, not evidence that they produce any specific outcome together
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