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Problems such as SIBO, altered intestinal microbiota, and delayed gastric emptying have added to the difficulties of oral therapy in PD, often culminating in commonly observed motor fluctuations such as delayed on or early-morning off sometimes associated with severe non-motor symptoms as well
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Studies demonstrate that the ability of animal species to protect mitochondrial DNA through glutathione-dependent mechanisms is directly proportional to longevity across species
Rusce, L., et al., Alpha lipoic acid administration improved both peripheral sensitivity to insulin and liver clearance of insulin reducing potential risk of diabetes and nonalcoholic fatty liver disease in overweight/obese PCOS patients
