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Funding This study was partially supported by grants from the National Institutes of Health (NS081740 and NS082184 to JZ) and the National Natural Science Foundation of China (No

Acta Biomater 77:311321

Post-exertional symptom worsening sometimes called a "crash" is a sign that activity has exceeded the patient's current capacity, and it is something we work actively to avoid rather than push through

Both are expected to move to Category 1 under the RFK reclassification, potentially mid-2026, which would open a legal compounding route with a physician's prescription