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GPX4, a key regulator of ferroptosis, converts lipid peroxides generated during this process into lipohydroperoxides, aided by GSH [10]
Dichloroacetate, a PDK inhibitor, induces the metabolic switch from glycolysis to OXPHOS to generate ROS accumulation, thereby facilitating ferroptosis [119] [Figure 4B]
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We computed the Hosmer-Lemeshow goodness-of-fit test for a generalized linear model fitted to binary response for the final models
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