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This test is based on the principle that unilateral MCAO induces ipsilateral rotations under ketamine
First, the heterogeneity between the model and the population is a key factor: preclinical studies are often conducted in animal models of a single disease (such as Diabetes Mellitus or senility), and the intervention dosage and duration are often optimized to highlight the muscle-preserving effect [60]
GLP-1 medications (semaglutide, tirzepatide, liraglutide) work through GLP-1 receptor activation in the gut, pancreas, and hypothalamus
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