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A root-cause approach is appropriate when pain persists despite medications, returns quickly after temporary relief, spreads beyond the original injury site, or when side effects begin to outweigh benefits
The addition of niacinamide is not just an arbitrary choice
Patient with metal implants, who would be restricted from MRI exam, can obtain advanced diagnostic imaging
Existing extended-release options, like weekly formulations of semaglutide and dulaglutide, have reduced injection frequency, and future innovations may include monthly formulations or implantable devices that deliver continuous therapy
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