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For eligible adults with clinically significant obesity, MHRA-approved options include semaglutide (Wegovy, assessed in NICE TA875) and tirzepatide (Mounjaro, assessed in NICE TA1026), both available through NHS pathways with appropriate clinical oversight
GLP-1 in the Brain: Stress, Satiety, and Food Noise Different regions in the brain control your desire to eat, and GLP-1 comes into play here in specific ways
While headaches and transient flushing are less common, they occur in fewer than 1% of cases
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