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Solubility: Soluble in sterile water, acetic acid, and physiological buffers (e.g., PBS) Description & Mechanism CJC-1295 without DAC is a synthetic analogue of growth hormonereleasing hormone (GHRH 129) incorporating amino acid substitutions designed to enhance stability relative to the native peptide
For example, different actions of GLP-1 receptor agonists such as delaying gastric emptying which leads to a prolonged feeling of fullness and reducing food intake lead to significant weight loss ( Endogenous GLP-1 has a short half-life since it is in 1-2 minutes degraded by the enzyme dipeptidyl peptidase-4 (DPP-4)
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