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Incidence and intensity of early dumping syndrome and its association with health-related quality of life following sleeve gastrectomy
They are systemic regulators, operating across the brain, cardiovascular system, skeletal muscle, bone, and adipose tissue simultaneously
Frigeni M, Balakrishnan B, Yin X, et al
Some researchers found that the expression of phosphofurin acidic cluster sorting protein 2 (PACS-2), a key regulator of MAM formation, was significantly reduced in renal tubules of DN patients, and PACS-2 was found to attenuate renal tubular injury through advancing MAM formation and mitophagy in a cellular model of HG-induced HK-2 and PACS-2 overexpression, and in a mouse model of STZ-induced PACS-2 knockout [121]
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