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Clinical trials reported substantial, dose-dependent weight loss , with the highest-dose groups showing average reductions of around 24% of body weight at 48 weeks
These reports are anecdotal and do not constitute clinical evidence
Sources: Mounjaro Uses, How it Works and Side Effects (2025) Diabetes UK (Accessed 6 October 2025) Tirzepatide (2025) NICE (Accessed 6 October 2025) Tirzepatide for managing overweight and obesity (2025) NICE (Accessed 6 October 2025) Tirzepatide as Compared with Semaglutide for the Treatment of Obesity (2025) New England Journal of Medicine (Accessed 6 October 2025)
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