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It is a PDE5 inhibitor that increases blood flow to the penis during sexual stimulation, helping achieve and maintain an erection
Research mechanism GLP-1 receptor activation in pancreatic -cells, hypothalamus, brainstem Glucose-dependent insulin secretion Delayed gastric emptying Central appetite suppression via hypothalamic and brainstem receptors Trial data summary STEP 1 trial (Wilding et al., NEJM 2021): mean body weight reduction of 14.9% at 68 weeks with weekly 2.4mg dosing
And this is important, because theres solid evidence that we begin naturally losing muscle around age 30at a decline of 3 to 5% of muscle mass per decade
GLP-1 medications work by mimicking the GLP-1 hormone (a satiety-inducing hormone), which signals fullness to the brain, slows gastric emptying, and helps stabilize blood sugar, explains Dr
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