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[36] [39] In animals and plants, the first two steps of the saccharopine pathway are catalysed by the bifunctional enzyme, -aminoadipic semialdehyde synthase (AASS), which possess both lysine-ketoglutarate reductase (LKR) (E.C 1.5.1.8) and SDH activities, whereas in other organisms, such as bacteria and fungi, both of these enzymes are encoded by separate genes
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Pharmacokinetics Blood EtOH and acetaldehyde pharmacokinetics were determined in male mice (1012 wk) 0, 1, 3, and 24 hr following an acute administration of EtOH (5 g/kg, i.p.)
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