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In the low-overdose patient (A), the maximum number of necrosed cells was 46 of 5,114 cells (0.89%) without zonation, which increased to 79 necrosed cells when applying 80% zonation (see Figure 4)

Glutathione biosynthesis occurs exclusively in the cytosol through a two-step ATP-dependent process

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Studies show that direct injection onto lyophilised powder reduces bioactivity by 1218% compared to wall-injection methods, and vigorous shaking causes 2535% degradation even when the solution appears visually clear