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In the brain, they influence hunger and reward signaling
A 2024 JAMA Ophthalmology study involving more than 37 million adults found a statistical association between semaglutide use and NAION
The limitations of this study can be attributed to several factors: First, as the FAERS database is a spontaneous reporting system, the quality and quantity of the information it contains are not strictly controlled
A 26-week clinical study comparing the effectiveness of liraglutide (1.8 mg once-daily) with exenatide (10 g twice-daily) indicates that patients treated with liraglutide had significantly greater reduction in HbA1c levels as well as significantly greater reduction in fasting plasma glucose levels as compared to patients treated with exenatide (Buse et al., 2009)
