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Peripherally, these agents induce significant weight loss, enhance insulin sensitivity, and reduce hepatic de novo lipogenesis
Nuclei were counterstained with DAPI (#422801, Biolegend, USA)
In addition, Fatty liver significantly elevates the risk of progressing from simple fibrosis to cirrhosis, and ultimately, liver cancer
Conservative therapies remain the foundation of treatment and should be optimized before or alongside any pharmacological interventions
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