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Red Flags That Require Urgent Attention Immediate evaluation is needed if the swelling is accompanied by high fever, rapidly progressive enlargement, signs of airway compromise, or severe local infection that could spread

Additionally, underlying medical conditionsincluding hypothyroidism, polycystic ovary syndrome, or sleep apnoeamay affect weight management outcomes and should be appropriately investigated and managed according to NICE guidelines

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Normal cells predominantly express MCT1, which confers a relatively limited capacity for lactate transport (126)