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Safety Revisited: Pancreas and Thyroid To close the loop on safety issues that have shadowed GLP-1 drugs: Pancreatitis/Pancreatic Cancer: Early on, especially around 2013, there were concerns that incretin therapies might increase pancreatitis risk or even pancreatic neoplasms (based on some animal data and analyses of FDA adverse event databases)

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Other laboratory research has also examined MT2s interaction with melanocortin receptors

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