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Thus, multienzyme-like reactions of NPs can simultaneously inhibit GPX4 and the FSP1-CoQ10H2 pathway in TNBC cells to promote ferroptosis, providing a promising avenue for the clinical treatment of drug-resistant tumors

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Upon glucose restriction, the p53 + cells were more sensitive to irinotecan as indicated by increased mitochondrial depolarization and cell death (Marx et al., 2022)

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