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Table 14: Results at Week 26 in a Trial Comparing TRESIBA to Sitagliptin in Adult Patients with Type 2 Diabetes Mellitus on OADs* Safety Outcomes Trial DEVOTE (NCT01959529) Cardiovascular Outcomes Trial Of TRESIBA Administered Once Daily Between Dinner And Bedtime In Combination With Standard Of Care In Subjects With Type 2 Diabetes And Atherosclerotic Cardiovascular Disease DEVOTE was a multi center, multi national, randomized, double blinded, active controlled, treat to target, event driven trial

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Analysis of these variables relies heavily on the clinician's impression and expertise, making the diagnosis inherently subjective