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Overall, we conclude that PC patients with low expression of VRK2 are sensitive to GSH-targeting therapy, while PC patients with high expression of VRK2 are re-sensitive to GSH-targeting therapy following VRK2 inhibition, indicating genetic aberrance of VRK2 expression stratifies the response of PC to metabolism-targeted therapies
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PMID: 52 HuWMLiMNingJZTangYQSongTBLiLZet al
By leveraging this mechanism, GLP-1 medications make you feel fuller sooner and longer after eating, which can lead to reduced calorie intake and subsequent weight loss
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