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GSH acts as the critical antioxidant to modulate the cellular redox state and is also a strong nucleophile
The cohort included two sub-groups ( n = 8 per sub-group) based on length of response to CAR T cells, with short-term responders (STR) having CD19+ leukemia relapse within 142 30 days following initial response and long-term responders (LTR) maintaining remission without subsequent therapy post-CAR T cell infusion
Gastrocutaneous (Skorjanec et al., 2009) and/or duodenocutaneous (Skorjanec et al., 2015) fistulas, as persistent lesions, are another instructive prototype of the two-ways model
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