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Topical treatments and mechanical therapies are also available

Higher cortical porosity leads to lower bone strength and a higher incidence of fragility fractures in this population

Interestingly, obesity itself is a major risk factor for non-alcoholic fatty liver disease (NAFLD), which affects approximately one quarter of the UK population according to the British Liver Trust

We first validated the buffering phenotype in the follow-up studies, in which SLC25A19 exhibited milder growth fitness defect compared to the control cells in the presence of complex III inhibitor antimycin, complex I inhibitor piericidin and complex V inhibitor oligomycin than in the regular culture condition (Supplementary Fig