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doi: 10.1111/ctr.14633

In addition, in cross-sectional analyses, it is not possible to determine whether the biomarkers reflect mechanisms driving disease development or are consequences of the diseases themselves

Patients who are particularly sensitive to GI side effects, who have a history of severe nausea with other medications, or who simply prefer a cautious approach may benefit from starting lower

It has three domains: a mutated GLP-1 (A8G) fragment with enhanced DPP-4 resistance, a humanized human serum albumin (HSA) nanobody that binds HSA to extend half-life by preventing rapid clearance, and a humanized GLP-1R nanobody that activates the GLP-1R signaling pathway upon dissociation from HSA