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CagriSema is an investigational once-weekly injectable weight-loss medication from Novo Nordisk that combines two active peptides, semaglutide and cagrilintide, in a single dose

It directly stimulates pro-opiomelanocortin/cocaine-and-amphetamine-regulated transcript (POMC/CART) neurons and indirectly inhibits neuropeptide-Y/agouti-related protein (NPY/AgRP) neurons through GABA neurotransmission, reducing appetite and promoting weight loss [40]

For research prospects, current anti-aging studies of the product are mainly conducted at the cellular and animal levels

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