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A baseline physical examination should include: Resting heart rate and blood pressure (sitting and standing) Cardiac auscultation to detect murmurs or irregular rhythms Assessment for signs of heart failure (peripheral edema, jugular venous distension) Baseline electrocardiogram (ECG) should be considered for patients with known cardiovascular disease, cardiac symptoms, or history of arrhythmias, rather than routinely for all patients over a certain age

The challenge here is accessibility

Some people who struggled with semaglutide actually do better on tirzepatide, and vice versa

Compounded semaglutide or tirzepatide shares the active ingredient but is a distinct preparation from a licensed 503A pharmacy not the FDA-approved brand and not a generic