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A blood test can determine if your child has FRAAs
Mitochondrial cytochrome P450 enzymes, embedded in the IMM with most of their protein body facing the matrix, bind a single heme moiety 88,89
Abbreviations LAB: Lactic acid bacteria GSH: Reduced glutathione GSSG: Oxidized glutathione ROS: Reactive oxygen species CDM: Chemically defined medium gshA: -glutamylcystiene synthetase gshB: glutathione synthetase gshF/gshAB: glutathione biosynthesis bifunctional fusion gene gor / gshR : glutathione reductase gpo: glutathione peroxidase gst: glutathione S-transferase cydDC: putative cysteine and glutathione importer
This could involve engineering GLP-1RAs with enhanced BRB-penetrating properties or creating dual-function molecules that combine metabolic regulation with specific ocular targeting
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