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Paradoxically, some people experience the opposite
Apremilast, an oral phosphodiesterase 4 (PDE4) inhibitor, in patients with moderate to severe plaque psoriasis: Results of a phase III, randomized, controlled trial (Efficacy and Safety Trial Evaluating the Effects of Apremilast in Psoriasis [ESTEEM] 1)
They are the prescription version of retinoids, which you can buy OTC
May have a positive effect on mood and emotional health
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