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To establish a connection with the NO-system, l-NAME (5 mg/kg intraperitoneally) (worsening) and/or L-arginine (100 mg/kg intraperitoneally) (beneficial effect) were given alone or together

Current trial data from the STEP UP trial noted injection site reactions in a slightly higher proportion of patients than the 2.4 mg dose

It works on three hormone receptors at once (GLP-1, GIP, and glucagon), which is why some people call it a triple agonist or Triple G. Its half-life sits around 6 days, so a single weekly shot is enough to keep blood levels steady

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