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AOD9604 is a synthetic fragment of human growth hormone designed to influence fat metabolism, whereas GLP1 medications like Semaglutide act on gut and brain hormone pathways to reduce appetite and improve blood sugar

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The same publication also detected an increased abundance of the genus Colidextribacter in patients with impaired intestinal permeability [38]: this taxon has previously been described to play a role in the increase of cellular oxidative stress capacity in a mice model, thus contributing to gut barrier impairment [38]