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In addition, the increased levels of IL-1 were also associated with loss of muscle mass, and its mechanism could be achieved by regulating the apoptosis of muscle cells and inhibiting the proliferation of muscle cells [22]

Additional Sources Larkin J, Chiarion-Sileni V, Gonzalez R, et al

Moreover, another study by Sagrillo-Fagundes and his group found that melatonin significantly regulated autophagy and inflammation in primary trophoblast cells that were exposed to a hypoxic/reoxygenation environment, mimicking preeclamptic pregnancy, thus reducing apoptosis in these cells

Presented for research literature review only Saluk-Juszczak J et al