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These findings indicate semaglutide's potential to mitigate antipsychotic-induced metabolic risks, supporting its consideration for high-risk patients with schizophrenia, prediabetes, and BMI 27 to prevent type 2 diabetes and cardiovascular disease, despite higher costs

Mechanism of Action A GLP-1 analog, semaglutide stimulates the bodys GLP-1 receptors to boost pancreatic insulin secretion in a glucose-dependent manner and reduce glucagon levels, thereby improving glycemic control