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The SURPASS trials demonstrated stable or improved kidney function in the tirzepatide groups compared to placebo, suggesting long-term kidney benefits that outweigh the short-term risks from GI-related dehydration
Note that the semaglutide dose in SURPASS-2 was 1 mg (not the 2 mg diabetes dose or 2.4 mg obesity dose), so these comparisons don't represent maximal semaglutide
Any of those can change the outcome on the day even if your timing is fine
The study helps to answer a common question: whether GLP-1 agonists can reduce the frequency of migraines, Cheng, who was not involved in the research, said
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