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Through NRF2-driven GSH synthesis, tumor cells are protected from oxidative stress, which contributes to chemotherapy resistance by reducing the cytotoxic effects of ROS generated during treatment

Supplementing with NAC NAC is commonly taken as a supplement to improve glutathione levels or for its own unique anti-inflammatory and mucolytic properties

Differential expression of glutathione S-transferase, glutathione peroxidase and [PMID: 2337897] Laboratory literature summary: Differential expression of glutathione S-transferase, glutathione peroxidase and glutathione reductase in normal and malignant research