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Future multi-region MRS studies examining GSH simultaneously in the thalamus, occipital cortex, and other brain regions within the same patients would help clarify whether GSH reduction is specific to the thalamus or represents a more widespread phenomenon

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ERK, extracellular regulated protein kinase

Moreover, GIPR-Ab/GLP-1 is detected in circumventricular organs in the brain and activates c-FOS in downstream neural substrates involved in appetite regulation