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Because mitochondria are the primary source of reactive oxygen species (ROS), mitochondrial iron levels need to be tightly regulated
Mater 29 (25), 1901417
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Three separate experiments were performed, once with 23 mice per group due to logistical issues, and twice with 5 mice, for a total of 1213 mice per treatment group as follows: vehicle (PBS) n = 12, L-carnitine alone n = 13, colistin alone n = 13, colistin and L-carnitine co-injection = n = 12
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