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Such analyses can be performed in epidemiological studies, such as in workers exposed to lead [302, 419], or in in vitro systems which can determine the molecular basis of apoptotic effects [420,421,422,423]
The GSTO1 C4-10 structure solved to 2.10 resolution has two residues (Y229 and W222) that differ from the 1EEM structure
This transport step is the rate-limiting bottleneck in fat oxidation: without adequate carnitine availability, fatty acids cannot efficiently enter the mitochondria for energy production regardless of how much stored fat is available
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