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You have a triple agonist with the strongest single-compound weight-loss record in modern obesity research, plus an amylin analog with a standalone double-digit result and a phase 3 combination precedent proving amylin adds to GLP-1
This approval marks the first FDA-approved oral GLP-1 weight loss pill , which is expected to significantly influence demand in 2026
Glucagon activation increases hepatic glucose output, stimulates thermogenesis (heat production), and promotes lipolysis (fat breakdown)
J Intern Med 229:1817
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