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Additionally, LET7(H290N) purified from Escherichia coli reduced the PPase activity in dephosphorylating p- nitrophenyl phosphate ( p NPP) in an in vitro phosphatase activity, compared with LET7 (Fig
Oikawa SY, Kamal MJ, Webb EK, McGlory C, Baker SK, Phillips SM
Interestingly, a fraction of OPCs in the adult brain remain at the stage of immature progenitors and can respond to neuronal activity by proliferation and differentiation (Gibson et al., 2014), to adapt myelination to the needs of active networks
This process is particularly pronounced when glutathione (GSH) is depleted or glutathione peroxidase 4 (GPX4), a key enzyme that prevents lipid oxidation, is inhibited [39]
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