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To address the difference in semaglutide dose between IcoSema and semaglutide alone, semaglutide exposure was dose-normalized
Tirzepatide activates GLP-1 receptors and glucose-dependent insulinotropic polypeptide, which helps reduce appetite and food intake and contribute to weight loss
EMBL-EBI ChEMBL
Baseline characteristics for the 579 randomized patients included 34% with hypertension, 26% with dyslipidemia, 10% with obstructive sleep apnea, and 2% with cardiovascular disease
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