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Patients with a personal history of medullary thyroid carcinoma (MTC) should discuss this with their specialist before considering GLP-1 medications
That popularity has led to a lot of exploration into the different mechanisms of delivery for the peptide, to find the right balance of primary effect and adverse side effects
Melanotan II still circulates in TRT circles for "aesthetic" purposes, but the side effects (nausea, spontaneous erections, darkening moles) and lack of safety data make it a hard pass unless you really want a tan that badly
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