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Because T4 is a small, naturally occurring peptide that functions across multiple tissues, it may offer a more practical therapeutic approach compared to complex interventions such as stem cell therapies
A dose that produces an effect in a mouse does not scale linearly to a human by body weight, and the research doses in this protocol are practitioner-derived conventions, not figures validated against human outcomes
Anal Biochem 98(1):154159 Massa CM, Liu Z, Taylor S, Pettit AP, Stakheyeva MN, Korotkova E, Popova V, Atochina-Vasserman EN, Gow AJ (2021) Biological mechanisms of S-nitrosothiol formation and degradation: how is specificity of S-nitrosylation achieved
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