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Constipation Slower digestion, reduced food intake, and lower fluid intake may contribute to constipation in some participants
Regular probiotic and digestive enzyme supplementation
PCSK5 plays a critical role in lipid metabolism 16 , cell proliferation, and migration 17 through the processing and conversion of various proteins 18
Holotoxin delivery and cell viability (CellTiter-Glo assay) 6His-tagged proteases fused to the BoNT translocation domain via a thrombin-cleavable linker were expressed and purified as described above
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