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10.1111/j.1540-8167.2007.00965.x 19
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So the timing of medications is very important for their effective outcome and safety.Few medications need to be taken on an empty stomach, like few thyroid medications, medications for gastritis, some of the anti-tubercular medications, some anti-diabetics, etc., which help in the absorption of medications into the blood.While some medications should be avoided on an empty stomach, such as antibiotics, vitamins, mineral supplements, etc., which might cause gastric irritation/GI intolerance (nausea, vomiting)
In case the study is on humans, the sample size must be calculated to achieve a statistical power of at least 80% [473]
