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However, despite their effectiveness, GLP-1 agonists are not without drawbackshigh cost, gastrointestinal side effects, long-term dependency, and concerns about sustainability once the drug is discontinued
Blood sugar spikes: GLP-1s help regulate glucose levels, so discontinuing the drug can cause blood sugar to rise, especially in people with Type 2 diabetes
CircABCB10 silencing inhibits the cell ferroptosis and apoptosis by regulating the miR-326/CCL5 axis in rectal cancer
This results in reduced appetite, increased feelings of fullness, and decreased food intake, promoting weight loss
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